Various polyols, such as sorbitol, mannitol or xylitol, can be found naturally in some fruits or vegetables in significant quantities. Polyols are principally used as sugar replacers in food products, a major advantage over intense sweeteners being their bulking property. Their energy cost is less than that of sugars. Although sugars’ caloric value is 4 kcal/g, that of polyols is only 2.4 kcal/g (European norms). Today, European regulation also recognizes the nutritional benefits of such molecules. In this article we review the scientifically demonstrated benefits of SweetPearl® maltitol for oral health.